The 10th Federation of the Asian and Oceanian Physiological Societies Congress

In conjunction with the 75^th Annual Meeting of the Korean Physiological Society

EXCO, Daegu, Korea, 1-4 November 2023

Education
1947-55 Emanuel School, London (A levels in Chemistry, Physics, Botany & Zoology)
1955-1958 University College London. BSc (1st Class honours) 1958. Class Prize in Physiology.
1958-1961. Bayliss-Starling Scholar, University College London.
1961 PhD Supervisor: O.F.Hutter (later Regius Professor of Physiology in Glasgow).
Academic Posts
1961—1963. Assistant Lecturer in Physiology, University College London.
1961—1963. Vice-Warden of Connaught Hall (University of London).
1963—1984. Fellow and Tutor, Balliol College, Oxford. University Lecturer in Physiology.
1969—1970. Visiting Professor and Visiting Scientist of the Canadian MRC.
1971—1989. Head (Praefectus) of the Balliol College Graduate Centre at Holywell Manor
1975—1985 Leader of MRC Programme Grant team.
1983—1985. Vice-Master of Balliol College
1984—2004 Burdon Sanderson Professor of Cardiovascular Physiology, Oxford University
1984—2004 Professorial Fellow, Balliol College.
2004-now Emeritus Professor of Cardiovascular Physiology, Oxford University
2004-now Emeritus Fellow of Balliol College, Oxford
2004-now Director of Computational Physiology, Co-Director of e-science centre, Oxford.
2003-2007 Adjunct Professor Xi’an Jiaotong University, Shaanxi province, China
2005-now Visiting Professor, Osaka University, Japan

Company Directorships
1984-now Chairman and Director, Oxsoft Ltd
1994-2003 Founder and Director, Physiome Sciences Inc

Editorships
1967-now Chief Editor, Progress in Biophysics and Molecular Biology
2001-2005 International Advisor, Tsinghua Science and technology
2004-2006 Chief Editor, Drug Discovery Today: Disease Models
2004-2006 Editorial Board, Transactions on Computational Systems Biology
2004-2007 Advisor to Board of Journal of Experimental Physiology
2005-2020 Chief Editor, Faculty of 1000, Physiology
2011-2017 Editor, Interface Focus

International Committees
1993-2001 Secretary-General of International Union of Physiological Sciences (IUPS)
2001-now Membre du Jury, Prix Lefoulon-Delalande, Academie des Sciences, Paris
2009-2017 President of the International Union of Physiological Sciences (IUPS)
National Committees
1994-2004 Member of government Advisory Group on Korea (DTI)
1986-2006 Executive Committee of Campaign for Science and Engineering (UK)
Main Previous Committees
MRC (former Chairman of Joint Dental Committee 1984-1990)
Member of Advisory Group on non-ionizing radiation (AGNIR), Health Protection Agency (HPA).
Royal Society Committees
Member of Council, Oxford University 1989-2004
Member of Systems Biology Committee, Academy of Medical Sciences and Academy of Engineering
Systems Panel of BBSRC

Publications
ARTICLES. Over 600 articles in academic journals, including Nature, Science, PNAS, Journal of
Physiology, Progress in Biophysics & Molecular Biology Listed on Google Scholar:
https://scholar.google.co.uk/citations?user=J6kLmsIAAAAJ&hl=en
Many articles in national press
BOOKS
Author or Editor of 13 books, including
The Initiation of the Heartbeat (OUP, 1975, 1979 and Japanese translation), sole author
Electric Current Flow in Excitable Cells (OUP 1975, 1988), author with JJB Jack and RW Tsien
The Logic of Life (OUP 1993), co-editor with CAR Boyd, and author
The Ethics of Life (UNESCO 1997) co-editor with J-D Vincent
The Music of Life (OUP 2006) sole author
La Musique de la Vie (Editions du Seuil, 2007 – French edition of The Music of Life))
La Musica de la Vida (Akal, 2008 – Spanish edition of The Music of Life))
La Musica della Vita (Bollati-Boringhieri, 2008 – Italian edition of The Music of Life)
⽣命の⾳楽：ゲノムを越える⽣物学 (Japanese edition of The Music of Life, 2009)
!"# $% (Korean edition of The Music of Life – Open Science, 2009)
⽣命的乐章 (Chinese edition of The Music of Life – 2010)
The Selected papers of Denis Noble CBE FRS. A journey in physiology toward enlightenment. Imperial
College Press 2012
Dance to the Tune of Life: Biological Relativity (CUP) 2016
The Language of Symmetry, Routledge. 2023
Dance to the Tune of Life (Japanese Translation) 2023
Understanding Living Systems, (with Raymond Noble), Cambridge University Press 2023

Honours and awards
1970 Scientific Medal of the Zoological Society.
1979 Elected Fellow of the Royal Society (FRS).
1982 Research Fellowship for Academic Staff (Medical Research Council).
1985 British Heart Foundation's biennial Gold Medal and Prize.
1985 Correspondant Etranger de l'Académie Royale de Médecine de Belgique.
1986 Fellow of University College London.
1988 Honorary Member of the Royal College of Physicians (Hon MRCP).
1989 Member of Academia Europaea
1989 Professorial Distinction Award, Oxford University
1991 Pierre Rijlant Prize (l'Académie Royale de Médecine de Belgique).
1993 Baly Medal of the Royal College of Physicians (London).
1993 Honorary Foreign Member of the Académie Royale de Médecine de Belgique.
1994 Honorary Fellow of the Royal College of Physicians (Hon FRCP)
1996 Honorary Member of the American Physiological Society
1997 Honorary Member of the Physiological Society (UK & Ireland)
1998 Honorary Member of the Physiological Society of Japan
1998 Appointed CBE in Queen’s Birthday Honours List, for ‘services to science’
1998 Visiting Professor at Johns Hopkins University, Baltimore, USA
1999 Founding Fellow of the Academy of Medical Science (FMedSci)
2000 Founding Fellow of the International Society for Heart Research
2001 Honorary Fellowship of the Institute of Physics and Engineering in Medicine
2003 Appointed Adjunct Professor Xi’an Jiaotong University, Shaanxi province, China (2003-2007)
2004 Honorary Degree of Doctor of Science by Sheffield University
2004 Awarded Russian Academy of Sciences Pavlov Medal at Russian Physiological Society Congress
2004 Hodgkin-Huxley-Katz Prize, The Physiological Society (UK)
2005 MacKenzie Prize, British Cardiac Society, May 2005
2005 Docteur Honoris Causa, Université de Bordeaux, September 2005
2008 Medal of Merit, EU-ISHR, Athens, May 2008
2008 Honorary Degree of Doctor of Science University of Warwick, July 2008
2010 Member of Slovenian Academy of Science
2012 Collaborative Professor, Osaka University, Japan
2013 Membro Straniero, Istituto Lombardo-Accademia di Scienze e Lettere
2022 Awarded Lomonosov Grand Gold Medal by the Russian Academy of Sciences

Named invited Lectures
1962 Invited Lecture, IUPS Congress, Leiden
1966. Darwin Lecture, British Association.
1977. Nahum Lecture, Yale University.
1977. Invited review lecture. IUPS Congress. Paris (delivered in French).
1979. Conférence invitée. Association des Physiologistes. (Delivered and published in French)
1981. Waller Lecture, London University
1983. Annual Review Lecture. The Physiological Society. (Published as The Surprising Heart)
1984. Withering Memorial Lecture. International Congress of Pharmacology. London
1985. Lettura F. Botazzi. Società Italiana di Fisiologia. Pisa. (Delivered in Italian).
1985. Ueda Lecture. Japanese Society of Electrocardiologists. Tokyo. (given partly in Japanese)
1987. Lloyd-Roberts Lecture, Royal Society of Medicine, London
1988. Allerdale-Wyld Memorial Lecture – Northern Industrial Societies.
1988. Bowden Lecture – University of Manchester Institute of Science and Technology
1989. Bacaner Research Awards lecture, University of Minnesota.
1989. Distinguished visiting lecturer at the Universities of British Columbia, Alberta and Calgary.
1989. Distinguished visiting professor at the State University of New York at Stony Brook, USA.
1990. Oliver Sharpey Lecture --- The Royal College of Physicians, London.
1990. Butland Visiting Professor at the University of Auckland, New Zealand.
1990. Annual Review Lecture, Korean Physiological Society (delivered partly in Korean).
1991. Invited lecturer at the 150th anniversary celebrations of the Académie Royale de Médecine de
Belgique, Brussels. (delivered in French)
1993. Annual Foundation Lecture of International Science Policy Foundation.
1994. First triennial Rijlant Lecture to International Congress of Electrocardiology (Japan).
1995. First annual lecture at UCL on disabled students in higher education.
1996. Frank May Public Lecture, Leicester University.
1996. Conference Claude Bernard, Societé de Physiologie, Lille, (delivered in French)
1996. Stevenson lecture, University of Western Ontario.
2003. Magnes Lecture, Hebrew University of Jerusalem and Israeli Physiological Society.
2003. Larmor Lecture, Queen’s University, Belfast.
2004. Conway Lecture, University College Dublin.
2004. Hodgkin-Huxley-Katz Prize Lecture, The Physiological Society.
2006. Woolmer Lecture, Institute of Physics and Engineering in Medicine, Cambridge 6 September
2006. Plenary Lecture, FAOPS Congress, Seoul, October
2007. Jacques Morgenstern Colloquium, INRIA Sophia-Antipolis
2007. Paton Lecture, The Physiological Society
2007. McDowall Lecture, King’s College London
2007 Distinguished Invited Lecture, EMBL Heidelberg
2008 Public Lecture, Museum of the History of Science, Oxford
2008 George Cecil Clarke Lecture, Nottingham University
2009 Foster Lecture, Cambridge University
2009 Kroto Lecture, Sheffield University
2010 Moe Lecture, Chicago
2012. Rupert Riedl Lecture, Vienna
2012. Plenary Lecture, Chinese Association of Physiological Sciences, Suzhou.
2013. President’s Lecture, IUPS, Birmingham
2013. Lecture to Istituto Lombardo, Milan (delivered in Italian)
Many other Congress and Symposia Plenary lectures. Denis Noble gives about many public invited
lectures per year in Universities, Congresses, Foundations and Societies worldwide.
Recent Funding
2003-2008 EPSRC eScience Pilot Project in Integrative Biology £2,798,950 (PI on interdisciplinary
grant)
Wellcome Trust Cardiac Physiome programme grant £1.2 million
EU 6th Framework Programme, 2004-2009, Biosimulation network Euros 300,000 2004-2009.
EU 7th Framework Programme PreDiCT 2008-2011 approx 4 million euros
EU 7th Framework Programme Virtual Human Network of Excellence. 2008-2013 approx 8 million
euros, part of Oxford led ICT grants totally 27 million euros.
British Heart Foundation, about £100,000
2013-2018 University of Oxford Innovative Systems Biology Project funded by Tsumura, £2million
Professional Societies
The Physiological Society
(Hon Secretary 1974—80; Foreign Secretary 1986—92; Honorary Member 1997)).
The Royal Society (Member of various committees).
The Royal College of Physicians (Honorary Fellow)
British Biophysical Society (past member of Committee)
British Cardiac Society
Mind Association
Académie Royale de Médecine de Belgique
Academia Europaea (past Convenor in Physiology and Biophysics)
CaSE, (Campaign for Science and Engineering founded as Save British Science, Founder and member
of Executive Committee)
American Physiological Society (Honorary Member 1996)
International Union of Physiological Sciences (IUPS) (Secretary-General, 1994—2001, President
2009-2017)
Japan Physiological Society (Honorary Member, 1998)
Academy of Medical Sciences (Founder Fellow, 1998)
International Society for Heart Research (Founding Fellow 2000)
Institute of Physics and Engineering in Medicine (Honorary Fellow)
Fellow, The Linnean Society of London, 2021.
Russian Academy of Sciences, Foreign Member 2022

Other interests and activities
Philosophy Publications in professional journals of philosophy, and books. See
https://www.denisnoble.com/western-philosophy/
https://www.denisnoble.com/philosophy-oriental/

Cooking French & Indian
Classical Guitar: player and owner of Rubio, Ramirez and Fischer guitars.
For music see website https://www.denisnoble.com/music/

Languages:
French – very highly fluent, able to give lectures and interviews without notes. Denis Noble was a
member of the Committee of the Maison Française d’Oxford and has broadcast frequently in France.
Italian – sufficient to give prepared lectures in Italian.
Occitan – Good knowledge of most dialects and speaker of Limousin; Denis Noble has appeared on
French Radio concerning Occitan language and music and has contributed to Occitan publications. He
is founder of The Oxford Trobadors, who interpret Occitan songs, medieval and modern.
Catalan, good reading ability
Portuguese, Good reading ability
Japanese – good knowledge of spoken and written language (including Kanji), sufficient to write and
deliver prepared speeches and short lectures in Japanese. Several publications in Japanese.
Korean – good knowledge of written Korean (Hangul) and some knowledge of Chinese script
(Hancha). Sufficient knowledge of spoken Korean to give a speech or introduction to a lecture. Denis
Noble was a UK Government Advisor on Korea.
Chinese – some reading knowledge (through Japanese and Korean characters, and study of medieval
Chinese medical texts)
Maori – delivered the reply to the Maori welcome (Powhiri) at the IUPS Congress in Christchurch,
New Zealand, 2001.
Others – some knowledge of many other languages (Denis Noble makes it a rule to learn something of
the language in any country he visits)
Citation statistics on google scholar: http://scholar.google.co.uk/citations?
user=UjxL_dUAAAAJ
May 2023:
Citations 33147
h-index 89
I10-index 287

Name : LUCIO I. M. COCCO
Website : https://www.unibo.it/sitoweb/lucio.cocco/en
Address : Cellular Signalling Laboratory, Department of Biomedical Sciences, University of Bologna, Via Irnerio, 48, 40126 Bologna, Italy
Tel : +39.051.2091639; +39.338.1194752 (mobile);

EDUCATION : 1976: M.D. University of Chieti (summa cum laude); 1978: Ph.D.- Sport Medicine, University of Chieti, School of Medicine.
POSITIONS HELD
1977-1979 : Assistant Professor at the Chair of Anatomy, University of Bologna; 1979-1982: Lecturer of Histology & Embryology, Medical School, University of Chieti, Italy;
1983-1985 : Associate Professor, Department of Anatomy, Medical School, University of Bologna, Italy; 1986-1990: Full Professor and Chairman, Chair of Anatomy, Department of Anatomical Sciences, Medical School, University of Chieti, Italy;
1986-1990 : Director of the Post-Graduate School in Hygiene, Medical School, University of Chieti, Italy;
1990-- : Professor, Cellular Signalling Laboratory, Dept. Biomedical Sciences, Medical School, University of Bologna, Italy;
1992-2018 : Dean of the Research Doctorate Programme in Biomedical Sciences, School of Medicine, University of Bologna, Italy;
2003-2009 : President of the PhD Programme Medical Biotechnology, University of Bologna
2012-- : Professor (visiting by invitation) at the University of Tsukuba, Ph.D. Programme in Human Biology, Japan;
2015-- : Perpetual Secretary of the Academy of Sciences-Physical Sciences of Bologna (founded in 1690);

SCIENTIFIC ACTIVITIES ABROAD
1979-1983 (sabbatical periods) : Visiting Scientist, Beatson Institute for Cancer Research, Glasgow, Scotland, UK;
1986 (sabbatical periods) : Visiting Professor, AFRC Babraham Institute, Cambridge, England, UK;

ASSIGNMENTS
1992-2010 : President of the Research Evaluation Panel of Biomedical Sciences, University of Bologna;
1994-1997 : Vice-President of the Italian Society for Histochemistry;
1995-2007: President of the Italian Red Cross Nursing School, Bologna;
2003-2006 : Member of the Panel 05 of the Italian CIVR (Italian Research Evaluation Committee);
2009-- : Member of the Evaluation Committee of the Fund for Scientific Research – FNRS, Belgium;
2015- : President of the Research Evaluation Committee of the Department of Biomedical and Neuromotor Sciences of the University of Bologna;
2015-- : Advisory board member of BK21+ Biomolecular Network program, Ulsan National Institute of Science and Technology, S. Korea.
2016-2017 : Member of the Committee (Biomedical Sciences) of Italian Ministry of Research for Programmes of National Interest, Italy
2016 : Member of the panel of Austrian Science Fund for the SFB 'Monarchies and Hierarchies in Shaping Chromatin Landscapes', Austria
2018-2019 : Member of the Committee (Biomedical Sciences) of Italian Ministry of Research for Programmes of National Interest, Italy
2018-2018 : Member of the Academic Senate of the University of Bologna;
2020- : Member of the Evaluation Panel of the University La Sapienza, Rome, Italy
2020- : Member of the Evaluation Committee of the Czech Science Foundation, Czech Republic
2021- : Scientific Curator of the Anatomical Wax Collection of the Museum of the University of Bologna;
2022- : President of the Italian Society for Anatomy and Histology

AWARDS
1996: Intl. J. Oncol. and Oncol. Reps. Award; 2001: Intl. J. Mol. Med. Award.
2012: Brain Poool Programme by S.- Korea Government
2016: Journal Lipid Research Lecturership – FASEB SRC/ASBMB, July/August 2016
2016: Lord Leitchfield Lecturership at the University of Oxford, October 2016
2018: Meet the Expert Award at the 2018 FASEB conference on Phospholipids: Dynamic Lipid Signaling in Health and Disease EDITORIAL BOARD: Editor-in-Chief of Advances in Biological Regulation; Associate Editor of Biochemistry and Cell Biology; Associate Editor Frontiers in Cellular Neuroscience Section Cellular Neuropathology); Associate Editor Biochemistry and Cell Biology; Guest Editor PNAS; Board Member: Cellular Signalling, J. Cellular Biochemistry , European J. Histochem., Oncology Rep. (1996-2003), Leukemia (2011-2013), Intl. J. Oncol., Intl. Arch. Biosci., Intl. J. Mol. Med., Recent Patents on Anti-Cancer Drug Discovery, Am. J. Blood Res., Cancer Rep., World J. Clin. Cases, Journal of Bioenergetics and Biomembranes, International Journal of Molecular Sciences, Netter Atlas of Human Anatomy (Intl. Advisory Board of 6th Edition). MEETINGS SYMPOSIA AND CONFERENCES -Since 1989 he has attended more than 150 international Meetings/Symposia/Conferences (such as FASEB Res. Conf., FEBS Meetings, Gordon Research Conf., Harden Conf., J. Monod Conf.; Eur. Symp. on Hormone&Cell.Regul., Keystone Symp., etc) as invited speaker. -2005: Founder and First Co-Chairman of the series of Gordon Research Conference “Signal Transduction Within the Nucleus”. RESEARCH INTEREST: His work (397 full length papers in peer reviewed Journals including New England Journal of Medicine, Nature, PNAS, J. Biol. Chem., Mol. Cell. Proteomics, FASEB J., Biochem. J., Blood, Leukemia, Stem Cells, J. Clinical Oncology, BBA Reviews on Cancer, Progress in Lipid Research, J. Lipid Research, J. Cell. Physiol, Molecular Psychiatry, EMBO Rep., etc.) covers the following fields: Structure and function of the nucleus and Inositide-dependet Signalling. He has discovered the existence of the nuclear signalling pathway via inositol lipid cycle and he is internationally recognised in the field of inositide signalling as “one the fathers of nuclear inositide signalling” for his seminal work in this issue. In particular since the last years his main interest is the study of the nuclear localisation and signalling activity of polyphosphoinositides. Namely he has furtherd the role of this signalling pathway in the nucleus during myogenic differentiation, giving new insight to its role in myotonic dystrophies, as well as during haemopoietic differentiation, envisaging the pathophysiological significance of nuclear phosphoinositide signalling in pathology. A full list of his articles and updated metrics are available at the Scopus link below: https://www.scopus.com/authid/detail.uri?authorId=7007037315&origin=cto

METRICS from Scopus : Documents: 398; Citations: 14163 h-index: 61

Shin was the founding Director of Brain Science Institute, KIST, and then Director of Center for Cognition and Sociality, IBS. He continues his research as an Honorary Fellow of IBS. He serves a CSO at SL Bigen Co. (Ltd.).
He studied neural mechanisms for animal behaviors, primarily focusing on the role of the thalamus in normal and diseased brains. His interest was on the regulation of intracellular Ca 2+ levels in brain cells. He utilized gene knock-out tools on genes such as voltage-gated Ca 2+ channels and PLC enzymes. Beginning in 2010 his research interest has evolved to neurobiology of social behaviors. He has pioneered to establish a behavioral paradigm, observational fear learning in mice, a rodent model for emotional contagion, basic form of affective empathy. This paradigm allowed, for the first time, to study affective empathy at the molecular and cellular levels.
He has been elected to be a member of the National Academy of Science, Republic of Korea, a foreign member at the National Academy of Science, USA, and an AAAS Fellow.